Micotil — put the benefits of the flex
dose to work in your operation

A proven cattle Bovine Respiratory Disease (BRD) treatment with a flexible dose range that allows you to manage risk and truckload weight variation more effectively

Micotil is the proven, long-lasting BRD treatment that offers a flexible, cost-effective dose range for both metaphylaxis and individual pull-and-treat therapy. Its flexible dose range (1.5 mL/cwt to 3.0 mL/cwt) allows stocker and feedlot producers to more effectively manage animal weight and risk variation within a truckload of incoming cattle.1

  • Micotil is an antibiotic approved for metaphylaxis that offers a flexible dose range
  • The flexible dose range helps ensure heavier cattle receive the most appropriate dose1
  • Micotil's flex dose allows you to better manage on-arrival animal weight and risk variation2
  • Micotil flex dose also delivers cost-effective pull-and-treat therapy in the hospital3

Commitment to Safety

Over the last two decades, Elanco has invested significant resources to ensure Micotil’s safe usage, including materials and training for distributors, veterinarians and producers. Among safety elements offered at no charge:

  • The SimcroTM Sekurus safety syringe, which has patented technology with self-tenting and needle-guard features. The syringe reduces the chance of accidental self-injection and withstands the most challenging environments at feed yards and stocker operations. To date, more than 30,000 have been distributed.
  • Extensive safety training is offered to more than 1,750 veterinarians and beef producers each year, including how to respond in case of accidental exposure to the product. 
  • Packaging to further enhance the safety profile, including an outer case that locks the bottle inside. 

Also, Elanco has voluntarily discontinued Micotil 300 Injection 100mL bottle in the U.S. due to a review of data that suggests customers utilizing this presentation have a higher incident rate of accidental human exposures.  

For more information on Micotil safety, please visit our Safe Handling and Use page.

Label information

Micotil is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica.

For the control of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in groups of beef and non-lactating dairy cattle, where active BRD has been diagnosed in at least 10% of the animals in the group.

Important Safety Information


See label for complete use information. Before using this product, it is important to read the entire product insert, including the boxed human warning.

  • Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
  • Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Do not use in automatically powered syringes. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice or cold pack to injection site while avoiding direct contact with the skin. Avoid contact with eyes.
  • Always use proper drug handling procedures to avoid accidental self-injection. Consult your veterinarian on the safe handling and use of all injectable products prior to administration.
  • For use in cattle or sheep only. Inject subcutaneously. Injection of this antibiotic has been shown to be fatal in swine and non-human primates, and may be fatal in horses and goats.
  • Do not use in female dairy cattle 20 months of age or older. Use in lactating dairy cattle may cause milk residues.
  • The following adverse reactions have been reported: in cattle: injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food and water consumption, and death.
  • Micotil has a pre-slaughter withdrawal time of 42 days.


  • CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.
  • Cattle intended for human consumption must not be slaughtered within 28 days of the last treatment.  
  • To assure both food safety and responsible use, treatment must be initiated within the first 45 days of the production period. The treatment should not occur concurrent with or following administration of an injectable macrolide, or within 3 days following administration of a non-macrolide injectable BRD therapy.
  • VFD expiration date must not exceed 45 days from the time of issuance. VFDs shall not be refilled.
  • Use only in cattle fed in confinement for slaughter.
  • Cattle with severe clinical illness should be evaluated for individual treatment with an alternative non-macrolide therapy.
  • Do not use in female dairy cattle 20 months of age or older or in veal calves.
  • Safety has not been established for cattle intended for breeding.
  • Do not allow horses or other equines access to feeds containing tilmicosin.

Dosage/Use Levels

Feed continuously for a single, 14 day period at 568-757 g/ton on a 100% dry matter basis of Type C medicated feed as the sole ration to provide 12.5 mg/kg of body weight/day.

1. Elanco Animal Health. Data on file.

2. Elanco Animal Health. Data on file.

3. Elanco Animal Health. Data on file.

Sekurus™ is a trademark of Simcro Limited.
Elanco®, Micotil® and the diagonal bar are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates. ©2017 Eli Lilly and Company, its subsidiaries or affiliates.