Effective 5-way viral and Lepto protection

Master Guard® vaccines contain a unique combination of killed and MLV components to provide reproductive pathogens and respiratory protection that’s proven safe and effective in cattle.

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Cow-calf and dairy producers alike depend on Master Guard vaccines to protect against common reproductive and respiratory pathogens in pregnant and open cattle.

To deliver effectiveness, Master Guard features killed antigens for BVD virus types 1a and 2, and IBR. The two MLV components — the same as found in Titanium — enhance cattle’s cell-mediated immune response for BRSV and PI3.

Lepto antigens add additional protection

Master Guard 10 HB also provides protection against five species of Leptospira spirochetes, including L. borgpetersenii serovar hardjo, the most common species of L. hardjo found in the United States.

Master Guard vaccines:

  • Can be given to cows and heifers at any stage of gestation
  • Allow the convenience of whole-herd vaccination in cattle 5 months of age and older

Trust Master Guard brand vaccines to provide the safety you want, and the protection you need against key pathogens.

Master Guard Information

Label Information

Important safety information

For all vaccine products

The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

For vaccination of healthy cattle five months of age or older.
Dose: 3 mL subcutaneous in the side of neck. See insert for full instructions.


1Immune response of calves to MLV and killed vaccines at branding and weaning — in the face of maternal antibodies. Study No. TR-20. Published by AgriLaboratories Ltd.