Pulmotil — 14 days of sustained BRD control in the palm of your hands

Effective BRD control isn't just a chute-side protocol anymore

Pulmotil® is an innovative bovine respiratory disease (BRD) treatment for groups of cattle in the early stages of a BRD outbreak that provides 14 days of sustained in-feed therapy, a practice that reduces stress associated with cattle handling.

Ideal for cattle not requiring a metaphylaxis treatment on arrival and/or when labor resources are limited, feeding Pulmotil means fewer pulls and less individual animal management.

  • Reduce the risk of a BRD outbreak once cattle are on-feed
  • Reduce the impact of subclinical BRD and associated economic losses
  • Reduce pulls with a 14-day sustained in-feed treatment
  • Reduce stress associated with animal handling by utilizing an in-feed management practice

Four-study registration summary — reduced pulls1

Cattle were allocated to a negative control or Pulmotil treatment when 10% or more of the calves received at the study sites showed active signs of BRD. Day 0 represents when the cattle started treatment; therapy stopped at the end of day 14.

  • Reduced BRD pulls (failures) by 35.6%
  • Fewer pulls starting at day four (Chart 1)
  • Reduced cumulative morbidity through day 28
  • No difference in daily feed intake was observed

Chart 1. Accumulated daily BRD-related morbidity

Implementing Pulmotil

To help ensure human food safety, the FDA established requirements for use of Pulmotil for the control of BRD. Be sure to work with your veterinarian to make sure the following requirements are met as you integrate Pulmotil into your BRD management program:

  • Contact your veterinarian for a Veterinary Feed Directive (VFD) and to develop a Pulmotil protocol for use once a 10% BRD diagnosis threshold has been reached in the group of cattle
  • Initiate the 14-day Pulmotil treatment within the first 45 days of the production period and only in groups of cattle that have not received an injectable macrolide antibiotic
    • Injectable macrolide antibiotics can be used once the Pulmotil treatment has ended
  • Pulmotil treatment can begin three days following the administration of a non-macrolide injectable BRD therapy
    • If the treatment must be initiated sooner, exclude calves treated with the injectable therapy from the group receiving Pulmotil

For Pulmotil: Feeds containing tilmicosin must be withdrawn 28 days prior to slaughter. CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

For the control of Bovine Respiratory Disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in groups of beef and non-lactating dairy cattle, where active BRD has been diagnosed in at least 10% of the animals in the group: Feed continuously for a single, 14-day period at 568 to 757 g/ton of tilmicosin (100% DM basis) in a Type C medicated feed as the sole ration to provide 12.5 mg/kg of body weight/day.

Important safety information

The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

Avoid inhalation, oral exposure and direct contact with skin or eyes.

VFD expiration date must not exceed 45 days from the time of issuance. VFDs shall not be refilled.

Use only in cattle fed in confinement for slaughter.
Cattle with severe clinical illness should be evaluated for individual treatment with an alternative non-macrolide therapy.
Do not use in female dairy cattle 20 months of age or older or in veal calves.
Safety has not been established for cattle intended for breeding.
Do not allow horses or other equines access to feeds containing tilmicosin.
Avoid inhalation, oral exposure and direct contact with skin or eyes. Keep out of reach of children.

1. Pulmotil 90 Freedom of Information Summary (NADA 141-064).

Elanco, Pulmotil and the diagonal bar are trademarks owned or licensed by Eli Lilly and Company, it's subsidiaries or affiliates.


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