Vaccine protection that’s easy on cattle1,2 and your bottom line

Unlike other respiratory disease vaccines, the Titanium® vaccine portfolio does not impact feed intake and results in little to no post-treatment side effects, so you can keep your cattle on track with health management solutions that don’t interrupt your day-to-day operations or affect your bottom line.1,2

With its consistent and proven BRD protection and competitive price point, Titanium provides you with an effective line of vaccines that makes sense for your health management protocols and budget.

Powerful immune response

Titanium’s Modified Live Vaccine (MLV) combination vaccines are excellent stimulators of cell-mediated immunity.3 The portfolio includes nine formulations ranging from a single antigen to a five-way combination product, giving you the disease protecting combinations you need to safeguard your cattle.

Studies document that Titanium vaccines protect against one or more of the viruses and bacteria associated with respiratory disease (see chart below) including:

  • BVD, types 1a and 2
  • IBR
  • PI3
  • BRSV
  • Five strains of Leptospira, including L. hardjo-bovis.3-7

View Image Larger

With USDA’s approval of four combination vaccines for nursing calves and pregnant cows, Titanium brand vaccines can now protect your whole herd against costly disease pathogens.8 Combinations currently approved for use in pregnant cows and nursing calves:

  • Titanium 5+PH-M
  • Titanium 5 L5 HB
  • Titanium 5
  • Titanium 4 L5

Keep your cattle healthy and on feed

You don’t have to choose one over the other — contact an Elanco Technical Consultant  or call your veterinarian to get BRD protection that doesn’t cost you performance.


Important Safety Information

For all vaccine products: The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions. Do not vaccinate within 21 days of slaughter.

Precautions: Do not use Titanium BRSV 3, Titanium 3 LP, Titanium 3, Titanium IBR LP
and Titanium IBR in pregnant cows or in calves nursing pregnant cows. Abortions
may result.

1. As measured by body temperature, feed intake, injection-site reaction or white blood cell count.
2. Terhaar, B. 2001. “Evaluating the effects of vaccine-induced stress on productivity.” Study No. TR-13. Published by Agri Laboratories Ltd.
3. Endsley, J. J., M. J. Quade, B. Terhaar, and J. A. Roth. 2002. “Bovine viral diarrhea virus type 1- and type 2-specific bovine T lymphocyte-subset responses following modified-live virus vaccination.” Vet. Ther. 3(4): 364-372.
4. Terhaar, B. 1999. “A comparison of Titanium 5 L5 and Bovishield 4 L5 following virulent infectious bovine rhinotracheitis virus challenge.” Study No. TR-04. Published by Agri Laboratories Ltd.
5. Data available upon request.
6. Ohnesorge, W. C. 1998. “Immunogenicity of a modified live bovine viral diarrhea virus, type 1 and type 2, vaccine following BVDV 890 (type 2) challenge.” Study No. 97-24.
7. "Immune response of calves to MLV and killed vaccines at branding and weaning – in the face of maternal antibodies.” Study No. TR-20. Published by Agri Laboratories Ltd.
8. Approved for pregnant cattle provided they were vaccinated subcutaneously with an MLV prior to breeding, according to label directions, with Titanium 3, 4 L5, 5 or 5L5 HB.