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Galliprant® (grapiprant tablets)

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Galliprant® (grapiprant tablets)

Treat Osteoarthritis (OA) When Dogs Need It

Safely treat canine OA from its earliest diagnosed stages

Galliprant is a first-in-class anti-inflammatory that targets the key receptor associated with canine OA pain, so you can start treatment from the earliest diagnosed stages. Give these dogs the relief they need and help keep them doing the things they love.

What is canine osteoarthritis?

Canine osteoarthritis is the most common cause of chronic pain in dogs1 and it doesn’t just occur in older, heavy dogs. It’s a painful disease that causes inflammation and swelling in a dog’s joints.

Early management and its benefits

Once pain sets in, a dog is less likely to move and may put on a few extra pounds. That can put more stress on joints and may lead to even more inflammation and pain. It’s a vicious cycle.

Why Galliprant?

  • Mode of action targets canine OA pain and inflammation while reducing the impact on GI, kidney and liver homeostasis2,3
  • Proven safe in a 9-month safety study in healthy dogs given up to approximately 15X the recommended therapeutic dose3,4
  • Most dogs can be dosed with a whole or half tablet
  • Please see Important Safety Information below

GALLIPRANT Group BottleBox 60mg 30ct rt1

If you're a veterinarian, click here to learn more.

If you're a pet owner, click here to learn more.

Indications

Galliprant is indicated for the control of pain and inflammation associated with osteoarthritis in dogs.

Important Safety Information

Not for use in humans. For use in dogs only. Keep this and all medications out of reach of children and pets. Store out of reach of dogs and other pets in a secured location in order to prevent accidental ingestion or overdose. Do not use in dogs that have a hypersensitivity to grapiprant. If Galliprant is used long term, appropriate monitoring is recommended. Concomitant use of Galliprant with other anti-inflammatory drugs, such as COX-inhibiting NSAIDs or corticosteroids, should be avoided. Concurrent use with other anti-inflammatory drugs or protein-bound drugs has not been studied. The safe use of Galliprant has not been evaluated in dogs younger than 9 months of age and less than 8 lbs. (3.6 kg), dogs used for breeding, pregnant or lactating dogs, or dogs with cardiac disease. The most common adverse reactions were vomiting, diarrhea, decreased appetite, and lethargy.

Click here or call 1-888-545-5973 for full prescribing information.

Citations

1 Fox SE. and Millis D. 2016. “Osteoarthritis: The Disease.” Multimodal Management of Canine Osteoarthritis: 24.

2 Kirkby Shaw, K., Rausch-Derra, L., and Rhodes, L. 2016. “Grapiprant: an EP4 prostaglandin receptor antagonist and novel therapy for pain and inflammation.” Vet. Med. Sci. 2: 3-9.

3 Rausch-Derra, L., Rhodes, L., Freshwater, L., et al. 2016. “Pharmacokinetic comparison of oral tablet and suspension formulations of grapiprant, a novel therapeutic for the pain and inflammation of osteoarthritis in dogs.” J. Vet. Pharmacol. Ther. March 29. DOI: 10.1111/jvp.12306.

4 Rausch-Derra, L., Huebner, M., and Rhodes, L. 2015. “Evaluation of the safety of long-term, daily oral administration of grapiprant, a novel drug for treatment of osteoarthritis pain and inflammation, in healthy dogs.” Am. J. Vet. Res. 76.10: 853-859.

Galliprant is a registered trademark of Aratana Therapeutics, Inc.