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Interceptor® Plus (milbemycin oxime/praziquantel)

Broad-spectrum parasite protection

You and your dog go everywhere. And, wherever you travel, you can trust the broad-spectrum parasite protection of Interceptor® Plus (milbemycin oxime/praziquantel).

Protects against 5 threats

Just one chicken-flavored chew each month protects your dog against five types of common (and potentially deadly) parasites:

  • Heartworm disease (Dirofilaria immitis)
  • Adult hookworm (Ancylostoma caninum)
  • Adult roundworm (Toxocara canis, Toxascaris leonina)
  • Adult whipworm (Trichuris vulpis)
  • Adult tapeworm (Taenia pisiformis, Echinococcus multilocularis, Echinococcus granulosus and Dipylidium caninum)

Is Interceptor Plus right for your dog?

Interceptor Plus is ideal for active dogs who love to go on adventures big and small.

What’s more, Interceptor Plus is a great value. Interceptor Plus provides broad-spectrum parasite control plus the flexibility to tailor flea and tick control to the season or whenever it’s needed.

And finally, Interceptor Plus is easy to dose – a chewable flavored with real chicken, willingly accepted by over 96% of dogs.

Interceptor Plus – Choose The Chew With More Protection Than Heartgard® Plus (ivermectin/pyrantel)

ICP-vs-HGP-Comparison chart

Five key threats to your dog’s health

Heartworm disease1

  • Heartworms are transmitted by mosquitoes and infection in dogs has been reported in all 50 states
  • Symptoms include coughing, sluggishness and difficulty breathing, although some dogs may show no signs at all.


  • A common intestinal parasite, one study showed as many as 29.8% dogs in the U.S. were infected2
  • Can be transmitted in many ways: ingestion of infected intermediate hosts, soil or feces, by microscopic larvae penetrating the pads of a dog’s paws or as pups via their mother’s milk3
  • Symptoms may include bloody diarrhea, weight loss and anemia3


  • As many as 12.5% of shelter dogs in the U.S. have roundworms (T. canis)2
  • There is high prevalence of infection, even in dogs routinely treated for intestinal parasites.
  • Symptoms may include diarrhea, vomiting, stunted growth, and a bloated belly. Heavy accumulations can cause death.4


  • A common parasite, approximately 18.7% of shelter dogs in U.S. are infected2 .
  • Contracted by dogs ingesting infective eggs (from soil or other contaminated or infested matter where infective eggs are found)5
  • Symptoms may include bloody diarrhea, dehydration and anemia5


  • Typically acquired by ingesting tapeworm larvae residing in a host such as rabbits, rodents or fleas6,7,8
  • Tapeworm segments can show up in a dog’s feces or on the fur under its tail

To learn more about Interceptor Plus, talk to your veterinarian or visit us online.

Important Safety Information

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, depression/lethargy, ataxia, anorexia, convulsions, weakness, and salivation. See product label for complete safety information.

1American Heartworm Society Current Canine Guidelines, 2014

2Blagburn, BL. August 2014. Proceedings of the American Association of Veterinary Parasitologists, 59th Annual Meeting. Abstract 65.

3 Accessed May 4, 2018.

4 Accessed May 4, 2018.

5 Accessed May 4, 2018.

6 Accessed May 4, 2018.

7 Accessed May 4, 2018.

8 Accessed May 4, 2018.

Interceptor is a trademark of Elanco or its affiliates.