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Elector® PSP

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Hemicell® (Endo-1,4-β-mannanase)

β-Mannans: the problem component in soybean meal
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Hemicell® (Endo-1,4-β-mannanase)

β-Mannans: the problem component in soybean meal

β-Mannans (beta-galactomannans) are antinutritive fibers found in common feed ingredients, including soybean meal and other leguminous feeds.1 β-Mannans have a molecular pattern similar to some pathogens, which triggers a Feed-Induced Immune Response (FIIR) in poultry.2-3 This unnecessary innate immune system stimulation consumes energy and other valuable nutrients.

Hemicell® (β-mannanase) is a nutrient-sparing enzyme that breaks down β-mannans
Most enzyme products are energy-releasing enzymes—they "open up" feed components the animal is unable to access on its own. Hemicell is different—it's a unique and patented energy-sparing enzyme. By breaking down β-mannans in soybean meal,3-4 Hemicell minimizes the metabolizable energy (ME) loss caused by the FIIR from β-mannans, allowing more energy to be available for growth and performance.4

Important Safety Information

The labels contain complete use information, including cautions and warnings. Always read, understand, and follow the labels and use directions.

Directions for Use

Hemicell is a unique and patented enzyme produced by fermentation of the bacteria, Bacillus lentus. The active ingredient is β-Mannanase.

Recommended use program: Use Hemicell in diets containing 12% SBM or higher.

Energy reduction (for high-energy diets): Improved performance allows for a reduction of dietary energy up to 40 kcal/lb.

Species: Broilers, Layers, Turkeys

Dosage: Hemicell Poultry Dosage

1Hsiao, H., Anderson, D. and Dale, N. 2006. "Levels of β-mannan in Soybean Meal." Poultry Sci. 85: 1430-1432.

2Ausubel, F. 2005. "Are innate immune signaling pathways in plants and animals conserved?" Nature Immunol. 6(10): 973-979.

3Zhang, L. and Tizard, I. (1996). “Activation of a mouse macrophage cell line by acemannan: The major carbohydrate fraction from Aloe vera gel.” Immunopharmacology. 35, 119-128.

4Korver, D. 2006. "Overview of the Immune Dynamics of the Digestive System." J. Appl. Poultry Res. 15: 123-135.

Hemicell is a trademark of Elanco or its affiliates.