Denagard Logo

Denagard® (tiamulin hydrogen fumarate)

Reduce the impact of two costly enteric diseases
Hemicell logo

Hemicell® (β-mannanase)

β-Mannans: the problem component in soybean meal
Kavault logo

Kavault® (Avilamycin)

Reduce the incidence and overall severity of E. coli scours
paylean logo

Paylean® (Ractopamine hydrochloride)

The choice for improved late-finishing performance and profitability
pulmotil logo

Pulmotil® (tilmicosin)

Control respiratory disease associated with Actinobacillus pleuropneumoniae or Pasteurella multocida
pulmotil AC logo

Pulmotil® AC (tilmicosin phosphate)

Go with the flow to help control swine respiratory disease (SRD)*
Skycis Logo

Skycis® (Narasin)

Ionophores: Innovation for a productive future
Tylan® Injection

Tylan® Injection

Effective at treating swine arthritis* in valuable breeding animals and finishers
Tylan® Logo

Tylan® Premix (Tylosin phosphate)

Proven control of ileitis* for dependable, reliable results

Tylan® Soluble (Tylosin tartrate)

Effective control of ileitis

Denagard Logo
Denagard® (tiamulin hydrogen fumarate)

Reduce the impact of two costly enteric diseases

Proven control and treatment of Swine Dysentery

Despite near eradication in the 1990s, Swine Dysentery (SD) has reemerged as an enteric disease capable of causing major biological and economic impact to swine herds.1 Highly contagious, SD is difficult to control once present, and immunity is slow to build in infected pigs.2 Correct diagnosis of SD is key, and implementing effective treatment, control or elimination programs helps your pigs become Full Value Pigs™.

Economic impact varies based on the severity and prevalence of the disease within an operation. The combination of treatment costs and death loss can cost producers thousands of dollars a year. A significant portion of that loss also comes from low average daily gain. It is estimated a producer loses between $11 and $17 for every infected animal.3

Denagard Premix controls SD associated with Brachyspira hyodsenteriae at 35 g/ton, and treats SD associated with Brachyspira hyodsenteriae at 200 g/ton fed for 14 days.

Utilize Denagard LC in drinking water at 3.5 mg/lb for five days for treatment of SD associated with Brachyspira hyodsenteriae.

Effective control of ileitis
Along with its proven treatment of SD, Denagard Premix also effectively controls ileitis. Ileitis, which is the number one enteric disease in the U.S., impairs cells associated with Lawsonia intracellularis from developing properly, which can reduce the pig's ability to absorb nutrients.4 Controlling ileitis also means nutrients can go towards growth, instead of fighting disease.

Denagard Premix controls ileitis associated with Lawsonia intracellularis when fed at 35 g/ton for not less than 10 days.

Degegard premix box Degegard LC box

Important Safety Information

The label contains complete use information, including cautions and warnings. Always read, understand, and follow the label and use directions.

Denagard® 10 Premix

  • Swine being treated with Denagard® (Tiamulin Hydrogen Fumarate) should not have access to feeds containing polyether ionophores (e.g. lasalocid, monesin, narasin, salinomycin, and semduramicin) as adverse reactions may occur
  • If signs of toxicity occur, discontinue use
  • Withdraw 7 days before slaughter at 200 g/ton and 2 days before slaughter at 35 g/ton
  • Keep out of reach of children. Avoid contact with skin. For use in swine only
  • The effects of Tiamulin Hydrogen Fumarate on swine reproductive performance, pregnancy and lactation have not been determined

Denagard® LC

  • Swine being treated with Denagard (Tiamulin Hydrogen Fumarate) should not have access to feeds containing polyether ionophores (e.g. lasalocid, monesin, narasin, salinomycin, and semduramicin) as adverse reactions may occur
  • If signs of toxicity occur, discontinue use of medicated water and replace with clean, fresh water
  • Withdraw medicated water 3 days before slaughter after treatment at 3.5 mg/lb and 7 days before slaughter following treatment at 10.5 mg/lb
  • Keep out of reach of children. Avoid contact with skin.
  • For use in drinking water of swine only. Prepare fresh medicated water daily. The effects of Tiamulin Hydrogen Fumarate on swine reproductive performance, pregnancy, and lactation have not been determined
  • If no response to treatment is obtained within 5 days re-establilsh the diagnosis

1. Duhamel, G. 2008. “Swine dysentery, a re-emerging disease in the US.” Proc. Am. Assoc. Swine Vet. 499-501.

2. McOrist, S. and Gebhart, C. 1999. “Porcine proliferative enteropathies.” Diseases of Swine 8th ed. Iowa State University Press. 521-534.

3. 2011. “The Costly Re-emergence of Swine Dysentery.” Headlines. Iowa Pork Producers Association. 10.2: 1-4.

4. Paradis, M. et al. 2005. “Subclinical ileitis produced by sequential dilutions of Lawsonia intracellularis in a mucosal homogenate challenge model.” Proc. AASV: 189-192.

Full Value Pigs and Denagard are trademarks of Eli Lilly and Company or its affiliates.