Denagard Logo

Denagard® (tiamulin hydrogen fumarate)

Reduce the impact of two costly enteric diseases
Hemicell logo

Hemicell® (β-mannanase)

β-Mannans: the problem component in soybean meal
Kavault logo

Kavault® (Avilamycin)

Reduce the incidence and overall severity of E. coli scours
paylean logo

Paylean® (Ractopamine hydrochloride)

The choice for improved late-finishing performance and profitability

Prevacent PRRS

Protect Your Piglets
pulmotil logo

Pulmotil® (tilmicosin)

Control respiratory disease associated with Actinobacillus pleuropneumoniae or Pasteurella multocida
pulmotil AC logo

Pulmotil® AC (tilmicosin phosphate)

Go with the flow to help control swine respiratory disease (SRD)*
Skycis Logo

Skycis® (Narasin)

Ionophores: Innovation for a productive future
Tylan® Injection

Tylan® Injection

Effective at treating swine arthritis* in valuable breeding animals and finishers
Tylan® Logo

Tylan® Premix (Tylosin phosphate)

Proven control of ileitis* for dependable, reliable results

Tylan® Soluble (Tylosin tartrate)

Effective control of ileitis

Prevacent PRRS

Protect Your Piglets


Porcine reproductive and respiratory syndrome (PRRS) is a costly disease that affects many stages of swine production. From reproductive failure in pregnant sows to respiratory disease in piglets, PRRS strikes swine operations right where it hurts most.

$1 BILLION estimated annual cost1 to the swine industry

$664 MILLION estimated production-related losses1

$478 MILLION estimated veterinary costs1

Prevacent PRRS - A Contemporary Solution for PRRS Today

Prevacent PRRS is a modified-live virus vaccine for the respiratory form of porcine reproductive and respiratory syndrome (PRRS) that is safe for use in piglets 2 weeks of age or older. With up to 26 weeks of demonstrated duration of immunity in pigs, Prevacent PRRS is the only Lineage 1 vaccine available on the market today.

CONTEMPORARY Lineage 1 vaccine

  • Prevacent PRRS is more homologous to Lineage 1 field strains MN184 and NC174 than any other modified-live PRRS vaccine on the market


  • Prevacent PRRS demonstrated protection against NADC20 and NC174 strains, resulting in a 93.2% reduction in lung lesions2,3

SAFE For your operation

  • Prevacent PRRS did not revert to virulence and exhibited limited transmission

CONTEMPORARY Lineage 1 vaccine

  • PRRS strains are classified into one of nine lineages based on their ORF-5 sequences. Over the years, these strains change and adapt, with the majority belonging to Lineage 14
  • Vaccine strains related to Lineages 5 and 8 were most prevalent during the 1980s and 1990s. However, since the mid-2000s, Lineage 1 PRRS strains have emerged as the most prevalent4
  • According to a presentation at the Allen D. Leman Swine Conference in September 2018, the majority of PRRS strains circulating in the U.S. are Lineage 15

Prev Dendrogram


Two challenge studies6,7 were performed to evaluate the efficacy of Prevacent PRRS against two PRRSv field strains. On average, pigs vaccinated with Prevacent PRRS had a 93.2% reduction in lung lesions (Chart 1) and a 286.4% increase in average daily gain (ADG).



  • PRRS increases mortality and reduces growth performance of wean-to-finish pigs.11 Prevacent PRRS has proven effective against the respiratory form of PRRS in healthy pigs at least 2 weeks of
  • Prevacent is a smooth vaccine that does not cause a reduction in growth performance as a result of vaccination, ensuring a strong start for just-weaned piglets. 2,3,8,9
  • With at least 26-weeks of demonstrated duration of immunity, a single 1 mL Prevacent dose is a safe and effective solution to get Full Value from the start.9,10
  • Prevacent is more homologous to Lineage 1 (the majority of field strains circulating today) field strains MN184 and NC174 than any other modified-live PRRS vaccine on the market.


Results showed:

  • No injection site reactions noted
  • Similar levels of adverse events as controls for each site
  • No vaccine-related adverse reactions noted

The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

1Holtkamp, D.J. (2013). Assessment of the economic impact of porcine reproductive and respiratory syndrome virus on United States pork producers. Journal of Swine Health and Production. 21(2). 12-84.

2Elanco Animal Health. Data on file.

3Elanco Animal Health. Data on file.

4Brar, M. S. (2015). Evolutionary diversification of type 2 porcine reproductive #and _ respiratory? syndrome= virus. J. Gen. Virology, 96:1510-1580.

5Paploski. I. (2018). Making epidemiological sense out of large datasets of PRRS sequences. Proc. Allen D. Leman Conference. September 11. 2018.

6Elanco Animal Health. Data on file.

7Elanco Animal Health. Data on file.

8Elanco Animal Health. Data on file.

9Elanco Animal Health. Data on file.

10Elanco Animal Health. Data on file.

11Iowa State University Porcine Reproductive and Respiratory Syndrome (PRRS) Accessed 2019 (v1.0)

Prevacent, Elanco, and the diagonal bar logo are
trademarks of Elanco or its affiliates