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Denagard® (tiamulin hydrogen fumarate)

Reduce the impact of two costly enteric diseases
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Hemicell® (β-mannanase)

β-Mannans: the problem component in soybean meal
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Kavault® (Avilamycin)

Reduce the incidence and overall severity of E. coli scours
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Paylean® (Ractopamine hydrochloride)

The choice for improved late-finishing performance and profitability

Prevacent® PRRS

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Pulmotil® (tilmicosin)

Control respiratory disease associated with Actinobacillus pleuropneumoniae or Pasteurella multocida
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Pulmotil® AC (tilmicosin phosphate)

Go with the flow to help control swine respiratory disease (SRD)*
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Skycis® (Narasin)

Ionophores: Innovation for a productive future
Tylan® Injection

Tylan® Injection

Effective at treating swine arthritis* in valuable breeding animals and finishers
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Tylan® Premix (Tylosin phosphate)

Proven control of ileitis* for dependable, reliable results

Tylan® Soluble (Tylosin tartrate)

Effective control of ileitis

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Pulmotil® AC (tilmicosin phosphate)

PRRS-Induced SRD Control from the Start

icon number 1
Pulmotil® AC quickly and effectively manages swine respiratory disease (SRD) associated with Mycoplasma hyopneumoniae (Myco) in the presence of PRRS without the need to formulate new rations, or invest the additional time and label associated with individual pig injections.
icon number 2
Porcine reproductive and respiratory syndrome virus (PRRSv) impairs natural disease-fighting macrophages, increasing susceptibility to other bacteria. Pulmotil’s unique mode of action concentrates in pulmonary macrophages, slowing the effectiveness of the PRRSv replication process and killing bacteria associated with swine respiratory disease.1, 2
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Pulmotil AC is the only FDA-approved aqueous concentrate that controls SRD associated with Myco in the presence of PRRSv in groups of swine in buildings where a respiratory disease outbreak is diagnosed.

Quick. Effective. Easy.

Pulmotil AC supplements host defenses, making neutrophils more effective. As the macrophages degenerate, Pulmotil releases — ready for a new macrophage.

After 24-hours of use:3

Pulmotil AC is visible in lung tissue, alveolar macrophages, bronchial epithelium:

Lung tissuLung tissue
Alveolar macrophageAlveolar macrophage
Bronchial epithelliumBronchial epithellium



Effectiveness in PRRSv and Myco Co-infection3

Lung lesion percentage results, following 5-day Pulmotil AC treatment:


Co-infections with PRRS and
secondary bacterial pathogens
exacerbate SRD outbreaks

Treatment-Group-bar-graph
Treatment group
Co-infection (Myco + PRRSv)
P-value = 0.004



No-Injection-icon
No injections;
easy mixing in water;*
easy start, easy stop
Calendar-icon
5 consecutive days,
start and stop as needed
Pig-weight-icons
25 lbs. pig** = 0.225 g / day
50 lbs. pig** = 0.225 g / day
Mixed in 1 gal of water = 0.75 g


*Must be diluted before administration to animals. Use within 24 hours of mixing with water.
**Intake assumptions: 25 lb pig = 2.5 lbs/day feed, 0.3 gal/day water; 50 lb pig = 3 lbs/day feed, 0.6 gal/day water; 75 lb pig = 4 lbs/day feed, 0.9 gal/day water; Lactating sow = 12 lbs/day feed, 6 gal/day water.

Important Safety Information

See label for complete safety and use information, including boxed human warning.

  • Before using this product, it is important to read the entire product insert, including the boxed human warning.

  • WARNING:

    Exposure to tilmicosin in humans has been associated with chest pain, increased heart rate, dizziness, headache, and nausea. Death has been reported following ingestion or injection of tilmicosin. Avoid direct skin and eye contact. In case of human exposure, call 1-800-722-0987, and consult a physician immediately.

    • Wear overalls, impervious gloves and eye protection when mixing and handling the product. Wash hands afer handling the product. Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water.
    • Caution: Pulmotil AC is to be used by, or on the order of, a licensed veterinarian.
      For use only in swine. Not for injection. Injection of tilmicosin has been shown to be fatal in swine and non-human primates, and may be fatal in horses and goats.
    • Swine intended for human consumption must not be slaughtered within 7 days of treatment.
    • Always treat the fewest number of animals necessary to control a respiratory disease outbreak. Prescriptions shall not be refilled.
    • Concurrent use of Pulmotil AC and another macrolide by any route, or use of another macrolide immediately following this use of Pulmotil AC is not advised.
    • Ensure that pigs have continuous access to medicated water during the treatment period.
      Monitor pigs for signs of water refusal and dehydration while being treated

1. Rossow, K.D. 1998. South Dakota State University. Porcine reproductive and respiratory syndrome. The American College of Veterinary Pathologists 35: 1-20.

2. Blais, J. 1994. Intracellular accumulation of tilmicosin in primary swine alveolar macrophages. Food and Agriculture Organization of the United Nations.

3. Freedom of Information Summary. 2014. NADA 141-361.

Pulmotil is a trademark of Elanco or its affiliates.