Safe Handling & Use Training

Reduce the potential for accidental injection of veterinary injectable products

Proper injectable drug use principles begin with you and your veterinarian

Elanco is highly committed to providing safe handling and use education, training and resources to veterinarians and beef cattle and dairy producers.

Worker safety

  • Prior to moving cattle, define a team lead
  • Do not work alone
  • Properly restrain all animals
  • Handle loaded syringes with care
  • Never carry loaded syringes in your coat or pockets
  • Keep needles properly covered until use
  • Keep children and bystanders out of work area
  • Identify an exit route
  • Be aware of uneven or changing walking surfaces
  • Clearly establish the team leader, roles and responsibilities
  • Evaluate the experience of those around you
  • Consult your veterinarian for safe handling and use training prior to administering injectable products

Animal safety

  • Use adequate facilities (i.e., squeeze chute, head gate)
  • Minimize handling stress in accordance with animal behavior
  • Adjust your activity with the temperament of each animal

Environmental safety

  • Post emergency procedures and contacts
  • Remove potential hazards in work area
  • Repair or remove broken equipment
  • Properly dispose of used needles and bottles
  • Recycle all injectable syringes and bottle packaging

Proper Micotil® (tilmicosin injection) handling and use procedures


Proper Micotil handling procedures

  • Storage of Micotil in a secure location to prevent the risk of misuse is recommended
  • Recommended storage includes a lockable cabinet or container or a secure storage room, depending on the amount of product in inventory
  • Keep full or empty Micotil bottles, used syringes and needles out of the reach of children and the general public
  • Read, understand and follow all label use directions
  • For subcutaneous use; do not use in automatically powered syringes
  • Use a 1/2" to 5/8", 16-18 gauge needle
  • Keep a protective cover on needles until ready to use
  • Never carry loaded syringes in pockets or clothing

Proper Micotil administration procedures

  • Properly restrain animal prior to administering Micotil
  • With a single hand on the syringe, insert the needle subcutaneously, at a top-down angle, while avoiding penetration of underlying muscle
  • Administer a single subcutaneous dose of 1.5 mL to 3 mL of Micotil per 100 lbs of body weight
  • Ensure proper disposal of needles, syringes and used bottles
  • If syringe is broken or damaged in any way, discontinue use immediately
  • Exercise caution and care when removing needle from syringe
  • Access to Micotil should be limited to personnel trained in safe handling and use procedures

Commitment to Safety

Over the last two decades, Elanco has invested significant resources to ensure Micotil’s safe usage, including materials and training for distributors, veterinarians and producers. Among safety elements offered at no charge:

  • The Simcro®Sekurus® safety syringe, which has patented technology with self-tenting and needle-guard features. The syringe reduces the chance of accidental self-injection and withstands the most challenging environments at feed yards and stocker operations. To date, more than 30,000 have been distributed. syringe sekurus.png
  • Extensive safety training is offered to more than 1,750 veterinarians and beef producers each year, including how to respond in case of accidental exposure to the product. 
  • Packaging to further enhance the safety profile, including an outer case that locks the bottle inside. 

Also, Elanco has voluntarily discontinued Micotil 300 Injection 100mL bottle in the U.S. due to a review of data that suggests customers utilizing this presentation have a higher incident rate of accidental human exposures.

Micotil is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica.

Important Safety Information


See label for complete use information. Before using this product, it is important to read the entire product insert, including the boxed human warning.

  • Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian
  • Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Do not use in automatically powered syringes. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice or cold pack to injection site while avoiding direct contact with the skin. Avoid contact with eyes.
  • Always use proper drug handling procedures to avoid accidental self-injection. Consult your veterinarian on the safe handling and use of all injectable products prior to administration.
  • For use in cattle or sheep only. Inject subcutaneously. Injection of this antibiotic has been shown to be fatal in swine and non-human primates, and may be fatal in horses and goats.
  • Do not use in female dairy cattle 20 months of age or older. Use in lactating dairy cattle or sheep may cause milk residues.
  • The following adverse reactions have been reported: in cattle: injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food and water consumption, and death.
  • Micotil has a pre-slaughter withdrawal time of 42 days.

In case of self-injection seek immediate medical attention and: REACH for and apply ice pack REFERENCE product label (link to label) "Note To the Physician" and/or product insert and provide to emergency medical personnel. REMEMBER to contact Rocky Mountain Poison and Drug Center (RMPDC) at 1-800-722-0987 or local poison control center at 1-800-222-1222.

Micotil is a trademark of Elanco or its affiliates.
Other company and product names are trademarks of their respective owners.